A systematic review of flaxseed effectiveness on infertility in animal model. Systematic Review
Resumo
According to the extensive studies carried out in the direction of the effectiveness of flax seed in solving various causes of infertility, the present study was conducted with the aim of investigating the effect of flax seed on infertility by a systematic review method. The search for studies in national and international databases was conducted in English and Persian without time restrictions. To evaluate the quality of the articles, the Cochrane Collaboration Risk of Bias tool and the Review Manager Program software (Revman 5.3) were used. The findings indicate that among the 1245 articles in the initial search, 56 articles (sample size: 4988) were included in the study. The articles were completed from 1998 to 2022 in Iran, America, Canada, Egypt and other countries of the world. Among the reviewed articles about the effect of flaxseed on the causes of infertility, 25 articles are about male and female reproductive system and sex hormones, 12 articles are about PCOS, 12 articles are about egg enrichment, two articles are about fertility power, two articles on uterine myoma and 1 article on cancer were studied. In most studies, the positive effect of flaxseed on infertility was confirmed. The available evidence shows the effect of flaxseed on different causes of infertility, but it is recommended to conduct more studies on different causes of male and female infertility on human samples with a strong methodology and appropriate sample size to ensure the effect of this plant on humans.
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Referências
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