Advances in the therapeutic approaches to feline sporotrichosis: A review

Emanueli Maria Freitas Rodrigues, Lara Cortez Passos, Luana Cortez Passos, Rebecca Carolina Oliveira da Costa, Sara Barbosa Costa, Nina Bezerra de Morais, Tiago Cunha Ferreira

Resumo


Feline sporotrichosis is an emerging zoonosis of growing concern, primarily transmitted through scratches, bites, or direct contact with secretions from infected cats. This mycosis significantly impacts public and animal health, particularly in urban areas with uncontrolled cat populations. Clinical signs typically include skin lesions, which may progress to systemic manifestations in severe cases. Standard antifungal treatment has proven effective in most cases, playing a crucial role in controlling disease progression and preventing zoonotic transmission. This literature review synthesizes available therapeutic strategies for the treatment of feline sporotrichosis to provide resources that assist professionals in improving the management of this mycosis. Despite significant advances in understanding and treating this condition, important knowledge gaps remain, particularly concerning the standardization of therapeutic protocols, the management of refractory cases, and the mitigation of treatment-associated adverse effects. Therefore, it is concluded that, despite advancements in available therapies, there is a continued need for additional clinical trials to establish more precise protocols for most of the therapeutic options discussed.


Palavras-chave


Fungal infection, Sporothrix spp., treatment

Referências


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