Metastatic cutaneous melanoma in equine: anatomopathological aspects
Resumo
Cutaneous melanoma is a neoplasm originating from melanocytes. In equines, a variable incidence of 6 to 14% of the total tegumentary neoplasms. The occurrence of metastasis is uncommon. In this sense, the objective was to describe a case of metastatic cutaneous melanoma in the equine species. A 15-year-old mixed-breed mare, died and was sent to perform necroscopic examination. During the processing of samples of various tissues and organs submitted to histopathological analysis. The main macroscopic alterations observed corresponded to proliferations in cutaneous glandular tissue of the udder, mammary lymph nodes, heart, lung, parietal pleura, liver and spleen, with sometimes blackened cutting surface. The morphological pattern, throughout the udder tissue extension, was compatible with melanoma. Histopathological evaluation of the two affected organs revealed a similar microscopic appearance. When associating the anatomopathological findings, a picture of metastatic cutaneous melanoma was defined. Melanoma should be considered as one of the possible diseases that affect the integument wrapping of the udder of mares of advanced age. A thorough evaluation of the animal is useful, since the metastatic potential is a real possibility.
Palavras-chave
Referências
CAMPOS, A. G. S. S.; SANTOS, R. A.; MOTA, A. E. R.; MAIA, F. C. L.; SOUZA, J.C.A.; AFONSO, J. A. B.; MENDONÇA, C. L. Melanoma equino. Ciência Veterinária nos Trópicos, v.11, n.2/3, p.76-80, 2008.
CARVALHO, F. K. L.; DANTAS, A. F. M.; RIET-CORREA, F.; ANDRADE, R. L. F. S; NOBREGA-NETO, P. I.; MIRANDA-NETO, E. G.; SIMÕES, S.V.D.; AZEVEDO, S. S. Estudo retrospectivo das neoplasias em ruminantes e equídeos no semiárido do Nordeste Brasileiro. Pesquisa Veterinária Brasileira, v.34, n.3, p.211-216, 2014.
JAIN, D.; SING, T.; KUMAR, N.; DAGA, M. R. Metastatic malignant melanoma in bone marrow with occult primary site – a case report with review of literature. Diagnostic Pathology, v.2, n.38, p.1-4, 2007.
KYM, D. Y.; ROYAL, A. B.; VILLAMIL, J. A. Disseminated melanoma in a dog with involvement of leptomeninges and bone marrow. Veterinary Pathology, v.46, n.1, p.80–83, 2009.
MACGILLIVRAY, K. C.; SWEENEY, R. W.; PIERO, F. D. Metastatic melanoma in horses. Journal of Veterinary Internal Medicine, v.16, n.4, p.452- 456, 2002.
MENDES, L. C. N. Mammary tumors. In: SPRAYBERRY, K. A.; ROBINSON, N. E. (Ed). Robinson´s - Current therapy in equine medicine. 7.ed. St. Louis: Elsevier, 2015. cap.101, p.432-434.
MENDES, L. C. N.; ARAÚJO, M. A.; BOVINO, F.; ROZZA, D. B.; MACHADO, G. F.; CADIOLI, F. A.; FEITOSA, F. F. L.; PEIRÓ, J. R. Clinical, histological and immunophenotypic findings in a mare with a mammary lymphoma associated with anaemia and pruritus. Equine Veterinary Education, v.23, n.4, p.177-183, 2011.
PATTERSON-KANE, J. C.; SANCHEZ, L. C.; UHL, E. W.; EDENS, L. M. Disseminated metastatic intramedullary melanoma in an aged grey horse. Journal of Comparative Pathology, v.125, n. 2-3, p.204–207, 2001.
PEREIRA, A. M. S. M. Tumores melanocíticos em equinos–estudo clínico, histopatológico e imunohistoquímico. Vila Real, 2011. 61p. Dissertação (Mestrado Integrado em Medicina Veterinária) - Universidade de Trás-os-Montes e Alto Douro, 2011.
RAMOS, A. T.; SOUZA, A. B.; NORTE, D. M.; FERREIRA, J. L. M.; FERNANDES, C. G. Tumores em animais de produção: aspectos comparativos. Ciência Rural, v.38, n.1, p.148-154, 2008.
REESINK, H. L.; PARENTE, E. J.; SERTICH, P. L.; ENGILES, J. B. Malignant fibrous histiocytoma of the mammary gland in a mare. Equine Veterinary Education, v.21, n.9, p.467-472, 2009.
RISSI, D. R.; FIGHERA, R. A.; IRIGOYEN, L. F.; LACORTE, F. D.; BARROS, C. S. L. Melanoma maligno anaplásico em um equino. Ciência Rural, v.38, n.7, p.2072- 2075, 2008.
SCOTT, D.; MILLER, W. Equine Dermatology. 2.ed. Maryland Heights: Elsevier, 2011. 536p.
SMIET, E.; GRINWIS, G. C. M.; VAN DEN TOP, J. G. B.; SLOET VAN OLDRUITENBORGH-OOSTERBAAN, M. M. Equine mammary gland disease with a focus on botryomycosis: A review and case study. Equine Veterinary Education, v.24, n.7, p.357-366, 2012.
SILVA, S. C. G.; ALVES, A. D. F.; RӦNNAU, M.; TORRES, M. B. A. M. Carcinoma de células escamosas em equino com metástase pulmonar: relato de caso. Revista Brasileira de Higiene e Sanidade Animal, v.9, n.4, p.689–698, 2015. http://dx.doi.org/10.5935/1981-2965.20150062
SMITH, S. H.; GOLDSCHMIDT, M. H.; MCMANUS, P. M. A. Comparative review of melanocytic Neoplasms. Veterinary Pathology, v.39, n.6, p.651–678, 2002.
SPRENGER, L. K.; GABARDO, L. B.; RISOLIA, L. W.; MOLENTO, M. B.; SILVA, A.W.C.; SOUSA, R.S. Frequência de neoplasias cutâneas em equinos: estudo retrospectivo do laboratório de patologia veterinária da universidade Federal do Paraná. Archives of Veterinary Science, v.19, n.3, p.81-86, 2014.
VALENTINE, B. A. Survey of equine cutaneous neoplasia in the Pacific Northwest. Journal of Veterinary Diagnostic Investigation, v.18, n.1, p.123–126, 2006.
Apontamentos
- Não há apontamentos.
Visitas