Aspectos da terapia etnofarmacológica associados à atividade antitumoral. Uma Revisão

Glauco Jonas Lemos Santos, Diana Célia Sousa Nunes Pinheiro

Resumo


O estudo etnofarmacológico contribui para a descoberta de novos fármacos e de forma especial, aqueles voltados para a terapia anticancer. Os tumores acometem diversos tecidos de forma benigna ou maligna. Nesta última situação inclui-se além do crescimento anormal das células, a invasão de novos tecidos em virtude da dispersão das células tumorais, conduzindo o indivíduo à morte em muitos casos. Uma vez que os medicamentos anticancerígenos afetam gravemente as células normais, ressalta-se que o uso de extratos de plantas e produtos derivados no tratamento do câncer é de fundamental valor no controle de doenças crônicas. A utilização de plantas medicinais estende-se por todos os continentes, variando na disponibilidade vegetal específica/nativa e nos valores culturais e históricos dos povos. A validação científica de preparações medicinais utilizadas popularmente acaba levando não só a confirmação de novas formas de se tratar o câncer, mas de forma paralela nos leva a compreender, por meio dos ensaios pré-clínicos, o mecanismo de ação de compostos bioativos sobre as células tumorais.

Palavras-chave


etnofarmacologia; fitoterápicos; cancer

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