Células-tronco mesenquimais: características, cultivo e uso na Medicina Veterinária

Gabrielle Rosemblit Martins, Maria Fátima da Silva Teixeira, Rosivaldo Quirino Beserra Junior, Ronaldo Pereira Dias, Tereza D’ávila de Freitas Aguiar, Rebeca Cavalcante Marinho, Ana Raquel Almeida Pinheiro

Resumo


As células-tronco mesenquimais são células adultas indiferenciadas com grande plasticidade, capazes de originar tecidos mesodermais e não mesodermais, produzindo qualquer tipo celular necessário num processo de reparação. Devido a essas características essas células vêm ganhando muito atenção das pesquisas voltadas tanto para humanos como para animais, buscando-se protocolos padrões de separação, cultivo e diferenciação das mesmas para que possam ser utilizadas em diversas terapias celulares. O principal foco atual de interesse da terapia celular é a medicina regenerativa, em que se busca a substituição de células ou tecido lesado, senescentes ou perdidos para restaurar sua função, sendo as terapias com células-tronco, as que despertam mais interesse na sociedade. Atualmente, as pesquisas em Medicina Veterinária têm utilizados camundongos, ratos, gatos, cães, cavalos, ovelhas e cabras, isolando esse tipo celular, principalmente, da medula óssea, tecido adiposo, cordão umbilical e fluido amniótico.

Palavras-chave


medula óssea; animais, terapias; multipotentes

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